Researchers announce the first peer-reviewed research outlining the successful transplant of genetically modified, clinical-grade pig kidneys into a brain-dead human individual, replacing the recipient’s native kidneys. These positive results demonstrate how xenotransplantation could address the worldwide organ shortage crisis.
Fear of needles is, for part of the population, the main reason for not having a Covid-19 vaccine. That fear is of all times, clearly demonstrated by the fact that needleless techniques have been developed for over 150 years. The current technology, developed by David Fernandez Rivas and his team, is safer than previous ones, it is better possible to steer the injection fluid and the depth it penetrates into the body. This is reason enough for researcher Jelle Schoppink to compare the different options, in a 'perspective paper' in Advanced Drug Delivery Reviews.
Changes are coming to cervical cancer screening for Island women, with a move from the traditional pap smear to HPV testing.
Analysis of the entire tumor RNA can detect more relevant genetic changes than traditional methods.
Melanoma cells release small extracellular packages containing the protein nerve growth factor receptor, which primes nearby lymph nodes for tumor metastases, according to a new study.
Analysis established a set of 15 biological markers found in the blood that can predict depressive symptoms.
“Swarm Learning” is a technology that enables cross-site analysis of population health data while maintaining patient privacy protocols to generate improvements in precision medicine. That’s the goal described by an international team of scientists who used this approach to develop artificial intelligence (AI) algorithms that seek out and identify lung disease, blood cancer, and COVID-19 data stored in disparate databases.
Utilizing cutting-edge proteomics, researchers have mapped the "tau interactome" uncovering new findings about the role of tau in neurodegenerative disease. Scientists found that mutant tau impacts the function of mitochondria in human neurons. They also suggest a mechanism for how tau gets released from neurons and spreads throughout the brain, a pathological process that is strongly correlated with disease progression.
Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition. A research team at Baylor College of Medicine and collaborating institutions investigated the function of the protein Rev-erbα/β, a key component of the circadian clock, on heart disease development in animal models and human patients.
For millions of patients who have lost limbs for reasons ranging from diabetes to trauma, the possibility of regaining function through natural regeneration remains out of reach. Regrowth of legs and arms remains the province of salamanders and superheroes.
But in a study published in the journal Science Advances, scientists at Tufts University and Harvard University’s Wyss Institute have brought us a step closer to the goal of regenerative medicine.